These letters are to the British geologist, Harry Govier Seeley. Lushington was apparently a friend or mentor, and he advises Seeley to become a geologist, and praises his poetry. Some of the letters concern paleontology, university education at Cambridge, and an observation on Robert Browning.

This collection consists of correspondence, manuscripts, drawings, diaries, notebooks, and photographs. Sanderson began his travels in the jungles of Asia and Africa before starting his formal schooling at Eton and Cambridge in the late 1920s and early 1930s. His papers reflect his interest in animals, jungles, and natural history. Late in his life Sanderson's interest turned to UFO's and he was the director of the Society for the Investigation of the Unexplained.

Adam Sedgwick (1785-1873, APS 1860), geologist, was an important figure in the development of the modern discipline of geology. He was educated at Cambridge, being ordained in 1817. An excellent field geologist, he did significant work interpreting complex old rock in such places as Devonshire (naming the Devonian Period after that location), Cornwall, and the Lake District, correlating his findings with strata in places such as Germany. Sedgwick first interpreted strata from the period he named Cambrian. He served in many professional organizations and was honored for his work with the Wollaston and Copley medals. Sedgwick, a Liberal in politics, served on committees that reformed the administration of university education. Despite being a friend of Charles Darwin's, Sedgwick was critical of the materialist bent of Darwinian thought. The 37 letters in the collection were acquired at various times, mainly through purchase, and assembled for the collection. The letters span the dates 1825-1870. Individually most letters are not especially significant, but collectively they touch on most aspects of Sedgwick's life and career. There are letters about Sedgwick's work on university reform, the Geological Museum at Cambridge, lectures, colleagues, travel, health, and family. Only one letter in the collection delves into detail about Sedgwick's geologic work.

This collection of correspondence and documents focuses on Roughton's prolific life's work on respiratory physiology. His specific work at Cambridge University from the 1920s to the 1960s, as well as interludes in the U. S. during World War II, are covered, as is the scientific milieu in which he worked. Some of the subjects or organizations for which there are documents, are: Bermuda and Naples Zoological Research Stations; British Glue and Gelatin Research Assoc.; Biochemical Journal; Cambridge Philosophical Society; Cambridge University Departments of Physiology (pre-1939) and Colloid Science (post-1940); Harvard Fatique Lab.; Medical research Council; Trinity College Cambridge.